[The content of dopamine and hormones of system "hypophysis - thyroid" in blood of nomadic, settled and local population of the Arctic]

Klin Lab Diagn. 2017;62(5):291-296. doi: 10.18821/0869-2084-2017-62-5-291-296.
[Article in Russian]

Abstract

The examination was applied to the groups of nomadic, settled aboriginal and local Caucasian population of the Arctic, permanently residing in the North. The study was carried out in the same period of the year - the period of increasing of duration of daylight hours. The study covered 253 individuals aged from 21 to 50 years. Despite differences in life-style of nomadic and settled aborigines, the similar signs were established consisting in the higher functional activity of hypophyseal section of the "hypophysis - thyroid" system against the background of lower content of auto-antibodies to thyroid peroxidase under increasing of the level of dopamine in blood as compared with local Caucasian population of the Arctic. The variation of analyzed parameters in aboriginal population depending on life-style also is demonstrated. So, nomadic aboriginal population is characterized by higher content in blood of global and free fractions of triiodothyronine, lower index of peripheral conversion of iodothyronines, increasing of level of dopamine and adenosine mono-phosphate. In case of settled aboriginal population increasing of content of global and free thyroxine is typical. In case of nomadic aborigines an expressed dissonance in content of iodothyronines is established: shifting of limits of variations of global and free triiodothyronine aside of higher bounds of standard at shifting of limits of variations of free fractions of thyroxine aside lower bounds of standard. The positive correlation relationships are registered between content of dopamine, thyroid hormones and adenosine mono-phosphate are registered. They are more expressed nomadic aboriginal population.

Keywords: adenosine mono-phosphate; auto-antibodies to thyreoperoxidase; dopamine; local population; nomadic aborigines; settled aborigines; the Arctic; thyroid hormones.

Publication types

  • English Abstract