The relationship between body mass index and preeclampsia: A systematic review and meta-analysis

Morteza Motedayen; Mohammad Rafiei; Mostafa Rezaei Tavirani; Kourosh Sayehmiri; Majid Dousti

doi:10.18502/ijrm.v17i7.4857

The relationship between body mass index and preeclampsia: A systematic review and meta-analysis

Int J Reprod Biomed. 2019 Jul 31;17(7):463-472. doi: 10.18502/ijrm.v17i7.4857. eCollection 2019 Jul.

Authors

Morteza Motedayen¹, Mohammad Rafiei², Mostafa Rezaei Tavirani³, Kourosh Sayehmiri⁴, Majid Dousti⁴

Affiliations

¹ Department of Cardiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
² Department of Biostatistics and Epidemiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
³ Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁴ Psychosocial Injuries Research Center, Department of Biostatistics, School of Public Health, Ilam University of Medical Sciences, Ilam, Iran.

Abstract

Background: One of the causes of maternal and fetal mortality and morbidity is pregnancy-induced hypertension, the most common form of which is preeclampsia that causes many complications for mother and fetus.

Objective: The aim of this systematic review and meta-analysis was to determine the relationship between body mass index (BMI) and preeclampsia in Iran.

Materials and methods: Using valid keywords in the SID database, PubMed, Scopus, data obtained from all the articles, which were reviewed in Iran between 2000 and 2016, were combined using the meta-analysis method (random-effects model) and analyzed using STATA version 11.1.

Results: A total number of 5,946 samples were enrolled in 16 studies with the mean BMI values of 25.13, 27.42, and 26.33 kg /m $^{2}$ in the healthy, mild, and severe preeclamptic groups, respectively.

Conclusion: The results of this study revealed that there is a significant relationship between BMI and the risk of preeclampsia, so it can be said that BMI may be one of the ways to diagnose preeclampsia.

Keywords: Body mass index; Iran; Meta-analysis.; Preeclampsia.

Publication types

Review