Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function

Rafael Pulido; Roland Lang

doi:10.3390/ijms20184372

Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function

Int J Mol Sci. 2019 Sep 6;20(18):4372. doi: 10.3390/ijms20184372.

Authors

Rafael Pulido^{1

2}, Roland Lang³

Affiliations

¹ Biomarkers in Cancer Unit, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain. rpulidomurillo@gmail.com.
² IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain. rpulidomurillo@gmail.com.
³ Institute of Clinical Microbiology, Immunology and Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany. roland.lang@uk-erlangen.de.

Abstract

Dual specificity phosphatases (DUSPs) constitute a heterogeneous group of enzymes, relevant in human disease, which belong to the class I Cys-based group of protein tyrosine phosphatase (PTP) gene superfamily [...].

Publication types

Editorial
Introductory Journal Article

MeSH terms

Disease Susceptibility
Dual-Specificity Phosphatases / chemistry
Dual-Specificity Phosphatases / genetics*
Dual-Specificity Phosphatases / metabolism*
Gene Expression Regulation
Humans
Immunomodulation
Signal Transduction
Structure-Activity Relationship

Substances

Dual-Specificity Phosphatases