Psoriasis precipitated by timolol eye drops. A series of eight cases

Australas J Dermatol. 2020 Feb;61(1):e91-e93. doi: 10.1111/ajd.13155. Epub 2019 Sep 6.

Abstract

Induction of psoriasis following administration of beta blocker containing eye drops has rarely been documented. We report eight cases of psoriasis triggered by timolol eye drops. Since the clinical and histopathological features of this drug reaction are indistinguishable from those of idiopathic psoriasis, a thorough drug history should be taken in all patients, especially elderly ones, with recent onset of psoriasis.

Keywords: beta blocker; drug-induced psoriasis; primary open-angle glaucoma; psoriasis; scalp psoriasis; timolol.

MeSH terms

  • Adrenergic beta-Antagonists / administration & dosage
  • Adrenergic beta-Antagonists / adverse effects*
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Glaucoma, Open-Angle / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Ophthalmic Solutions
  • Psoriasis / chemically induced*
  • Timolol / administration & dosage
  • Timolol / adverse effects*

Substances

  • Adrenergic beta-Antagonists
  • Ophthalmic Solutions
  • Timolol