Venous Thromboembolism Following Abdominal Cancer Surgery in the Korean Population: Incidence and Validation of a Risk Assessment Model

Ann Surg Oncol. 2019 Nov;26(12):4037-4044. doi: 10.1245/s10434-019-07633-z. Epub 2019 Sep 5.

Abstract

Background: A cancer patient slated for abdominal surgery is considered to be at moderate to high risk for developing venous thromboembolism (VTE), but the incidence is quite low in Korean patients. Most risk assessment models and recommendations for VTE management are from Western reports, however they possibly overestimate the risk of VTE in the Korean population.

Methods: We retrospectively reviewed the medical records of 1966 patients who were diagnosed with abdominal organ cancer and required surgical treatment.

Results: Each patient was rated using the Caprini risk scoring model. The mean score was 7.5 ± 0.7 points; 98.4% of patients were classified as high risk for VTE. Symptomatic VTE occurred in eight patients, and the overall incidence was 0.4%. The mean Caprini score for VTE patients was 8.8 ± 1.9 points. In the group with scores between 5 and 9 points, the incidence was 0.3-0.5%, while in patients with scores > 10 points, the incidence of VTE was found to be 1.12%.

Conclusions: The risk stratification system in the Caprini scoring model needs to be modified based on the actual incidence in the Korean population.

Publication types

  • Validation Study

MeSH terms

  • Abdominal Neoplasms / pathology
  • Abdominal Neoplasms / surgery*
  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Models, Statistical*
  • Postoperative Complications*
  • Prognosis
  • Republic of Korea / epidemiology
  • Retrospective Studies
  • Risk Assessment / methods*
  • Risk Factors
  • Surgical Procedures, Operative / adverse effects
  • Surgical Procedures, Operative / methods*
  • Venous Thromboembolism / epidemiology*
  • Venous Thromboembolism / etiology