Heart failure caused by VGAM: a lesson for diagnosis and treatment from a case and literature review

J Matern Fetal Neonatal Med. 2021 Jul;34(14):2384-2390. doi: 10.1080/14767058.2019.1665013. Epub 2019 Sep 18.

Abstract

We describe the case of a neonate with signs of heart failure. Echocardiography showed a structural normal heart shape with left ventricular dysfunction. At 2 months of age, a vein of Galen arteriovenous malformation was diagnosed through a brain magnetic resonance imaging. Embolization therapy was accomplished and a clinical and neurological follow-up was started. This clinical case highlights how important it is considering an intracranial cause in the differential diagnosis of neonatal congestive heart failure (CHF). We performed a narrative minireview of the literature about treatments and outcome of this malformation in association to CHF, to point out how complex the diagnosis of vein of Galen aneurysmal malformation (VGAM) may be and how an early diagnosis is important for its management.

Keywords: Bregmatic fontanel auscultation; cardiac failure; endovascular treatment; neonate; vein of Galen malformation.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cerebral Veins*
  • Embolization, Therapeutic*
  • Heart Failure* / diagnosis
  • Heart Failure* / etiology
  • Heart Failure* / therapy
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Vein of Galen Malformations* / diagnosis
  • Vein of Galen Malformations* / diagnostic imaging