Prevalence of Ruptured Intracranial Aneurysms in a Tertiary Care Hospital of Nepal

JNMA J Nepal Med Assoc. 2019 May-Jun;57(217):168-171. doi: 10.31729/jnma.4328.

Abstract

Introduction: Intracranial aneurysms affect 3-8 percent of the world's population, with ruptured aneurysms being the most common cause of subarachnoid hemorrhage. The sensitivity of Computed Tomography Angiogram in diagnosing intracranial aneurysm is 97%. The aim of our study is to find out the prevalence of ruptured intracranial aneurysms among all the admitted cases encountered in our hospital.

Methods: A descriptive cross-sectional study was done at Upendra Devkota Memorial National Institute of Neurological and Allied Sciences from 2016 to 2018. Convenience sampling method was done. In order to detect the site and size of aneurysms, 16 slice Siemens Computed Tomography with Computed Tomography angiogram was used. Ethical approval was obtained from the Institutional Review Committee at Upendra Devkota Memorial National Institute of Neurological and Allied Sciences. Based on demographic data and computed tomography angiography findings, various morphometric parameters along with demographic parameters were considered for the study.

Results: Among 10,856 cases, prevalence of ruptured intracranial aneurysms were found in 42 (0.386%) [Confidence Interval= 0.395 to 0.377]. Among 42 cases, Middle Cerebral Artery aneurysm was present on 16 (39.02%) followed by Anterior Communicating Artery on 14 (34.14%), then Posterior Communicating Artery on 5 (12.19%). The largest neck and dome size were seen in basilar tip aneurysm with size of 11mm and 8mm respectively. The most common type was Fischer grade 4.

Conclusions: The prevalence of ruptured intracranial aneursyms were found to be higher as compared to the other international studies.

Keywords: Computed tomography angiogram; intracranial aneurysm; subarachnoid hemorrhage..

MeSH terms

  • Adult
  • Aged
  • Aneurysm, Ruptured / diagnostic imaging
  • Aneurysm, Ruptured / epidemiology*
  • Computed Tomography Angiography*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / epidemiology*
  • Male
  • Middle Aged
  • Multidetector Computed Tomography
  • Nepal / epidemiology
  • Prevalence
  • Sensitivity and Specificity
  • Tertiary Care Centers