Neurosyphilis presenting as pure cerebellar ataxia: an atypical manifestation

BMJ Case Rep. 2019 Aug 31;12(8):e231058. doi: 10.1136/bcr-2019-231058.

Abstract

Neurosyphilis has become an uncommon diagnosis in the current era. Neurological manifestations of syphilis usually lie within the spectrum of meningovascular syphilis, tabes dorsalis or general paresis of the insane. Although sensory ataxia may occur as part of spinal cord involvement, cerebellar ataxia has been rarely described as a manifestation of neurosyphilis. In this report, we describe a rare case neurosyphilis presenting in the form of a pure pancerebellar syndrome of subacute progression.

Keywords: brain stem/cerebellum; infection (neurology); meningitis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Ceftriaxone / therapeutic use
  • Cerebellar Ataxia / microbiology*
  • Cerebellar Ataxia / therapy
  • Diagnosis, Differential
  • Dysarthria
  • Gait Ataxia
  • Humans
  • Male
  • Middle Aged
  • Neurosyphilis / complications*
  • Neurosyphilis / drug therapy
  • Physical Therapy Modalities
  • Treponema pallidum

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone