PET/CT Specificities in 90Y Imaging Post Radioembolization

PET Clin. 2019 Oct;14(4):469-476. doi: 10.1016/j.cpet.2019.06.001. Epub 2019 Aug 6.

Abstract

This article presents a comprehensive review of the 90Y PET/CT challenges in imaging post liver radioembolization. Specificities of the different PET systems are identified. Conclusions are drawn to help the design of phantom validation studies, quantification of intrahepatic activity, assessment of tumor dosimetry, and checking of extrahepatic sphere delivery in clinical routine.

Keywords: Dosimetry; Liver radioembolization; PET; Quantification; Yttrium-90.

Publication types

  • Review

MeSH terms

  • Brachytherapy / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / mortality
  • Liver Neoplasms / radiotherapy*
  • Male
  • Monitoring, Physiologic / methods
  • Phantoms, Imaging
  • Positron Emission Tomography Computed Tomography / methods*
  • Radiotherapy Dosage
  • Survival Analysis
  • Treatment Outcome
  • Yttrium Radioisotopes / therapeutic use*

Substances

  • Yttrium Radioisotopes