Contact-free endoscopic photoacoustic sensing using speckle analysis

J Biophotonics. 2019 Dec;12(12):e201900130. doi: 10.1002/jbio.201900130. Epub 2019 Sep 16.

Abstract

Photoacoustic endoscopy (PAE) is an emerging imaging modality, which offers a high imaging penetration and a high optical contrast in soft tissue. Most of the developed endoscopic photoacoustic sensing systems use miniaturized contact ultrasound transducers or complex optical approaches. In this work, a new fiber-based detection technique using speckle analysis for contact-free signal detection is presented. Phantom and ex vivo experiments are performed in transmission and reflection mode for proof of concept. In summary, the potential of the technique for endoscopic photoacoustic signal detection is demonstrated. The new technique might help in future to broaden the applications of PAE in imaging or guiding minimally invasive laser procedures.

Keywords: laser surgery; photoacoustic endoscopy; remote sensing; speckle.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / diagnostic imaging
  • Animals
  • Endoscopy*
  • Image Processing, Computer-Assisted
  • Phantoms, Imaging
  • Photoacoustic Techniques / methods*
  • Signal-To-Noise Ratio
  • Swine