Spectroscopic signature of the pathological processes of carious dentine based on FTIR investigations of the oral biological fluids

Pavel Seredin; Dmitry Goloshchapov; Yuri Ippolitov; Jitraporn Vongsvivut

doi:10.1364/BOE.10.004050

Spectroscopic signature of the pathological processes of carious dentine based on FTIR investigations of the oral biological fluids

Biomed Opt Express. 2019 Jul 17;10(8):4050-4058. doi: 10.1364/BOE.10.004050. eCollection 2019 Aug 1.

Authors

Pavel Seredin^{1

2}, Dmitry Goloshchapov¹, Yuri Ippolitov³, Jitraporn Vongsvivut⁴

Affiliations

¹ Department of Solid State Physics and Nanostructures, Voronezh State University, Voronezh, University Sq. 1, 394018, Russia.
² Ural Federal University, 19 Mira Street, Ekaterinburg, 620002, Russia.
³ Department of Pediatric Dentistry with Orthodontia, Voronezh State Medical University, Voronezh, Studentcheskaya st. 11, 394006, Russia.
⁴ Australian Synchrotron (Synchrotron Light Source Australia Pty LTD), 800 Blackburn Rd, Clayton, VIC 3168, Australia.

Abstract

The aim of our work is to find a spectroscopic signature of the pathological processes of carious dentine based on the investigations of the molecular composition of the oral biological fluids with the use of FTIR synchrotron techniques. This complex analysis of the obtained data shows that a number of signatures are present only in the spectra of dentine and gingival fluids from the patients developing caries of the deep dentine tissues. The detected features and complex analysis of the quantitative and qualitative data representing signatures of the development of oral cavity pathologies can enhance the quality of dental screening.