Translation of Patient-Reported Outcomes in Oncology Clinical Trials to Everyday Practice

Ann Surg Oncol. 2020 Jan;27(1):65-72. doi: 10.1245/s10434-019-07749-2. Epub 2019 Aug 26.

Abstract

Purpose: Clinical trials in oncology evaluating the effects of patient-reported outcomes (PRO) collection have found that monitoring of symptoms with PROs is associated with improved clinical care through reduced acute care utilization and decreased patient symptom burden. This educational review will evaluate strategies for systematic PRO integration into everyday oncology clinical practice.

Methods: We outline key considerations for using PROs in clinical practice, highlighting evidence from published studies. We also discuss the benefits and challenges of PRO implementation in oncology.

Results: Implementing PRO collection in clinical practice can improve care delivery and facilitate patient-centered clinical research. Considerations for using PROs in clinical practice include choice of instrument, method of delivery, and frequency of query. Challenges with implementing systematic PRO collection include the costs and resources needed for implementation, impact on clinical workflow, and controlling/monitoring physician burnout.

Conclusions: While challenges exist in terms of financial resources and staff participation/burnout, patient-reported outcomes in clinical practice provide a number of benefits, including symptom monitoring, clinical research, and potential real-time personalized clinical-decision support.

MeSH terms

  • Humans
  • Neoplasms / psychology
  • Neoplasms / surgery*
  • Patient Participation / statistics & numerical data*
  • Patient Reported Outcome Measures*
  • Patient-Centered Care / standards*
  • Practice Guidelines as Topic / standards*
  • Quality of Health Care / standards*
  • Quality of Life*
  • Treatment Outcome