Prospects and Problems of Cancer Genome Analysis for Establishing Cancer Precision Medicine

Cancer Invest. 2019;37(9):427-431. doi: 10.1080/07357907.2019.1661428. Epub 2019 Sep 9.

Abstract

The genome represents a design for creating the body, with each one being different. In cancer genomic medicine, many genes are simultaneously examined using mainly cancer tissues (the oncogene panel test), and gene mutations are revealed. Cancer treatments are then initiated according to each individual's constitution and medical condition based on gene mutations. A system for cancer genome medical treatment is currently being developed. In the treatment of several types of cancer, the "oncogene test with an oncogene companion diagnosis" is already being performed as a standard test using cancer tissue to detect one or more gene mutations. On June 1, 2019, the cancer gene panel test was covered by the national health insurance system in Japan, and a system to initiate cancer genome medical treatment has begun. The prospects and problems associated with cancer genome medicine are discussed herein.

Keywords: gene mutation; genome medicine; panel test; precision medicine.

Publication types

  • Review

MeSH terms

  • Genomics / methods*
  • Health Policy
  • Humans
  • Japan
  • Mutation
  • National Health Programs
  • Neoplasms / genetics*
  • Precision Medicine