Dual Invasive Fungal Infection Presenting with Cervical Myelopathy

Charles A Miller; John J Delaney; A Jesse Schuette

doi:10.1016/j.wneu.2019.08.056

Dual Invasive Fungal Infection Presenting with Cervical Myelopathy

World Neurosurg. 2019 Nov:131:227-229. doi: 10.1016/j.wneu.2019.08.056. Epub 2019 Aug 19.

Authors

Charles A Miller¹, John J Delaney², A Jesse Schuette²

Affiliations

¹ Division of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA. Electronic address: Charles.a.miller5@gmail.com.
² Division of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

PMID: 31437516
DOI: 10.1016/j.wneu.2019.08.056

Abstract

Disseminated fungal infections are often seen in immunocompromised patients. Here we present a case of a previously healthy woman presenting with cervical myeloradiculopathy found to have two separate fungal infections in the setting of depressed CD4 cell counts and a genetic mutation predisposing to invasive fungal infections.

Keywords: CARD9; Cervical myelopathy; Fungal infection; ICL.

Publication types

Case Reports

MeSH terms

Antifungal Agents / administration & dosage
Cervical Vertebrae*
Chronic Pain / microbiology
Cryptococcosis / complications
Cryptococcosis / drug therapy*
Drug Administration Schedule
Drug Therapy, Combination
Female
Histoplasmosis / complications
Histoplasmosis / diagnosis
Histoplasmosis / drug therapy*
Humans
Invasive Fungal Infections / drug therapy*
Magnetic Resonance Imaging
Middle Aged
Neck Pain / microbiology
Radiculopathy / drug therapy
Radiculopathy / microbiology
Spinal Cord Compression / microbiology
Spinal Cord Compression / surgery*
Tomography, X-Ray Computed

Substances

Antifungal Agents