Abstract
A phytochemical investigation on the whole plant of Plantago maxima Juss. ex Jacq led to the isolation of a new and rare chlorinated iridoid glycoside named plantomoside (1), along with three known compounds, geniposidic acid (2), 10-deoxygeniposidic acid (3), and viteoid II (4). The structure of 1 was determined through 1 D and 2 D NMR spectroscopic data analysis, HR-ESI-MS, and acid hydrolysis.
Keywords:
Plantaginaceae; Plantago maxima; iridoid glycoside.
MeSH terms
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Animals
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Cell Death / drug effects
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Cell Line, Tumor
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Chlorine / chemistry*
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Humans
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Iridoid Glucosides / chemistry
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Iridoid Glucosides / isolation & purification
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Iridoid Glycosides / chemistry
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Iridoid Glycosides / isolation & purification*
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Iridoid Glycosides / pharmacology
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Lipopolysaccharides / pharmacology
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Mice
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Nitric Oxide / biosynthesis
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Phytochemicals / chemistry
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Phytochemicals / isolation & purification
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Phytochemicals / pharmacology
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Plantago / chemistry*
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RAW 264.7 Cells
Substances
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Iridoid Glucosides
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Iridoid Glycosides
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Lipopolysaccharides
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Phytochemicals
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geniposidic acid
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Nitric Oxide
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Chlorine