Mother's Touch: Milk IgA and Protection from Necrotizing Enterocolitis

Vanessa P Dunne-Castagna; Diana H Taft

doi:10.1016/j.chom.2019.07.013

Mother's Touch: Milk IgA and Protection from Necrotizing Enterocolitis

Cell Host Microbe. 2019 Aug 14;26(2):147-148. doi: 10.1016/j.chom.2019.07.013.

Authors

Vanessa P Dunne-Castagna¹, Diana H Taft²

Affiliations

¹ Department of Food Science and Technology, University of California, Davis, Davis, CA 95616, USA; Department of Nutrition, University of California, Davis, Davis, CA 95616, USA.
² Department of Food Science and Technology, University of California, Davis, Davis, CA 95616, USA. Electronic address: dhtaft@ucdavis.edu.

PMID: 31415742
DOI: 10.1016/j.chom.2019.07.013

Abstract

Human milk feeding is associated with lower rates of necrotizing enterocolitis (NEC), but an understanding of mechanism is lacking. In recent work, Gopalakrishna et al. report that human infants who develop NEC first experience an increase in Enterobacteriaceae in the portion of the microbiota not bound to IgA.

MeSH terms

Animals
Dysbiosis / prevention & control
Enterobacteriaceae / pathogenicity
Enterocolitis, Necrotizing / epidemiology
Enterocolitis, Necrotizing / microbiology
Enterocolitis, Necrotizing / prevention & control*
Humans
Immunoglobulin A / therapeutic use*
Infant
Infant, Newborn
Milk, Human / immunology*
Mothers
Touch

Substances

Immunoglobulin A