Microscopic investigations and pharmacognostic techniques for the standardization of Caralluma edulis (Edgew.) Benth. ex Hook.f

Microsc Res Tech. 2019 Nov;82(11):1891-1902. doi: 10.1002/jemt.23357. Epub 2019 Aug 15.

Abstract

Herbal medicines frequently suffer with quality controversies because of similar species or varieties. This often leads to sophistication or admixture of the crude drug as they share various look alike physical features. Commercially, stalks of Caralluma edulis are commonly adulterated with other species because of their analogous morphology. In the present research, the microscopic standardization of the drug was performed by structural, histological, and anatomical features. Pharmacognostical characterization was carried out by physicochemical (moisture content, swelling index, pH value, ash values, and extractive values) and fluorescence analysis. The chemical characterization by UV-Visible, Fourier transform infrared spectroscopy, and high-performance liquid chromatography was also performed that disclosed the chief phytoconstituents of the herbal drug. The above mentioned constraints, being reported for the first time in C. edulis, are substantial in establishing the microscopic and pharmacopoeial standards for future identification and authentication.

Keywords: Caralluma edulis; microscopy; pharmacognostic; standardization.

MeSH terms

  • Apocynaceae / anatomy & histology*
  • Apocynaceae / classification
  • Chromatography, High Pressure Liquid
  • Pharmacognosy
  • Plant Leaves / anatomy & histology
  • Plant Preparations / chemistry*
  • Plants, Medicinal / anatomy & histology*
  • Plants, Medicinal / classification
  • Spectroscopy, Fourier Transform Infrared

Substances

  • Plant Preparations