Reliability and validity of Chinese version of a tool to assess the quality of life in idiopathic pulmonary fibrosis in patients with interstitial lung disease

Rui-Li Pan; Jeffrey J Swigris; Yan-Wei Zhao; Ai-Min Guo; Qing Wu; Si-Jia Li

doi:10.1016/j.ijnss.2018.11.005

Reliability and validity of Chinese version of a tool to assess the quality of life in idiopathic pulmonary fibrosis in patients with interstitial lung disease

Int J Nurs Sci. 2018 Nov 21;6(1):38-42. doi: 10.1016/j.ijnss.2018.11.005. eCollection 2019 Jan 10.

Authors

Rui-Li Pan¹, Jeffrey J Swigris², Yan-Wei Zhao¹, Ai-Min Guo³, Qing Wu³, Si-Jia Li³

Affiliations

¹ Department of Respiratory Medicine, Peking Union Medical College Hospital, Beijing, China.
² Autoimmune Lung Center and Interstitial Lung Disease Program, National Jewish Health, 1400, Jackson Street, Denver, CO, USA.
³ School of Nursing, Peking Union Medical College, Beijing, China.

Abstract

Objective: This paper aims to determine the reliability and validity of the Chinese version of a tool that assesses the quality of life in idiopathic pulmonary fibrosis (cATAQ-IPF) in patients with interstitial lung disease (ILD).

Methods: We used the process of scale introduction to establish cATAQ-IPF. The content validity of the scale was evaluated by six experts. A total of 92 patients with ILD completed the cATAQ-IPF, St. George's respiratory questionnaire (SGRQ), and The Medical Research Council dyspnoea scale at the baseline, and 15 patients completed cATAQ-IPF at the follow-up period 2 weeks later. Thus, yielding data were used to assess various psychometric properties of cATAQ-IPF. Intraclass correlation coefficient (ICC), Cronbach's α coefficient, content validity index (CVI), item-level CVI (I-CVI), Pearson's coefficients, criterion-relation validity, and known-group validity were used for data analysis.

Results: The cATAQ-IPF showed excellent test-retest reliability (ICC = 0.95), except for the therapy domain (Cronbach's α = 0.60) and acceptable internal consistency (Cronbach's α = 0.96 for the total). The scale-level CVI was 0.80, and the I-CVI was in the range of 0.78-1.00. The total cATAQ-IPF score was strongly correlated with the SGRQ total score (r = 0.71, P < 0.01). The cATAQ-IPF score of patients with ILD was 250.74 ± 47.39, and that of patients with IPF was 287.90 ± 22.56. Patients with IPF possessed considerable impairments in health-related quality of life according to the cATAQ-IPF score (t = 4.94, P < 0.01).

Conclusions: The cATAQ-IPF is a reliable and valid instrument for the evaluation of quality of life of Chinese patients with various forms of ILD.

Keywords: ATAQ-IPF; ATAQ-IPF, a tool to assess quality of life in IPF; CVI, content validity index; HRQL, health related quality of life; Health related quality of life; I-CVI, item-level content validity index; ICC, intraclass correlation coefficient; ILD, interstitial lung disease; IPF, idiopathic pulmonary fibrosis; Interstitial lung disease; MRC dyspnoea scale, Medical Research Council dyspnoea scale; Reliability; S-CVI, scale-level content validity index; SF-36, The Medical Outcomes Short Form 36; SGRQ, St. George's respiratory questionnaire; Validity.