Determination of activity meter settings for the PET nuclides 44Sc and 89Zr

E García-Toraño; E Sanz Romero; A Martínez Ortega

doi:10.1016/j.apradiso.2019.108829

Determination of activity meter settings for the PET nuclides ⁴⁴Sc and ⁸⁹Zr

Appl Radiat Isot. 2019 Nov:153:108829. doi: 10.1016/j.apradiso.2019.108829. Epub 2019 Jul 30.

Authors

E García-Toraño¹, E Sanz Romero², A Martínez Ortega²

Affiliations

¹ Laboratorio de Metrología de Radiaciones Ionizantes, CIEMAT, Spain. Electronic address: e.garciatorano@ciemat.es.
² Unidad de Aplicaciones Biomédicas y Farmacocinética, CIEMAT Avda, Complutense 40, Madrid, 28040, Spain.

PMID: 31394471
DOI: 10.1016/j.apradiso.2019.108829

Abstract

Radionuclide activity meters depend on "calibration setting numbers" that are specific for a certain combination of radionuclide, volume and geometry. This work describes their determination for two PET emerging nuclides (⁴⁴Sc and ⁸⁹Zr), three commercial activity meters (CAPINTEC CRC15 BETA, ATOMLAB BIODEX 500 and VEENSTRA VDC 405) and two geometries: 1 mL plastic syringes and 5 mL glass vials. For ⁴⁴Sc, only values for the dial setting for 5 mL ampoules were reported previously and its use for the assayed geometries would lead to significant differences. For ⁸⁹Zr more data were available in the literature, and results are provided for new geometries. All results rely on the absolute standardisation in activity of solutions of both radionuclides.

Keywords: Activity meters settings; Dose calibrator settings; Sc-44; Zr-89.