Pictorial review on abdominal applications of ferumoxytol in MR imaging

Abdom Radiol (NY). 2019 Oct;44(10):3273-3284. doi: 10.1007/s00261-019-02163-4.

Abstract

Though gadolinium-based contrast agents are the most widely used contrast media in MR for clinical use, problems with nephrogenic systemic fibrosis and tissue deposition render their safety debatable, at least in a selected patient population. Ferumoxytol has the potential to be used as an alternate contrast medium for various clinical applications across multiple organs. It has prolonged intravascular signal and delayed intracellular macrophage uptake which are unique properties compared to gadolinium-based agents. This pictorial review aims to review the current and potential clinical applications of ferumoxytol as a contrast agent in abdominal MR imaging.

Keywords: Contrast media; Ferumoxytol; Magnetic resonance imaging; USPIO.

Publication types

  • Review

MeSH terms

  • Abdomen / diagnostic imaging*
  • Contrast Media / administration & dosage*
  • Ferrosoferric Oxide / administration & dosage*
  • Humans
  • Magnetic Resonance Imaging / methods*

Substances

  • Contrast Media
  • Ferrosoferric Oxide