Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam

Vet Med Sci. 2019 Nov;5(4):512-516. doi: 10.1002/vms3.189. Epub 2019 Aug 2.

Abstract

Background: The Mekong Delta of Vietnam is a hotspot of antimicrobial use (AMU), but there is no information on the quality of the labelling and strength of antimicrobial products used in poultry production.

Methods: Based on a large random sample of farms, we identified the 20 most used antimicrobial products in the area, and investigated their antimicrobial active ingredient (AAI) content by UPLC-MS/MS (91 analytical tests).

Results: Only 17/59 (28.8%) batches contained all AAIs within 10% of the declared strength. Worryingly, 65.0% products provided in their label preparation guidelines for both therapeutic and prophylactic use. Withdrawal times for both meat and eggs were stated in 8/20 (40%) products.

Conclusion: Results highlight deficiencies in quality and labelling contents that undermine authorities' efforts to discourage inappropriate use of antimicrobials.

Keywords: Vietnam; animal production; antimicrobials; poultry; veterinary.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / therapeutic use
  • Chickens*
  • Chromatography, High Pressure Liquid / veterinary
  • Drug Labeling / statistics & numerical data*
  • Tandem Mass Spectrometry
  • Vietnam

Substances

  • Anti-Bacterial Agents