HIV and Chagas Disease Coinfection, a Tractable Disease?

Open Forum Infect Dis. 2019 Jul 1;6(7):ofz307. doi: 10.1093/ofid/ofz307.

Abstract

We present 2 patients born in Argentina who were newly diagnosed with advanced HIV disease and Chagas disease reactivation with central nervous system involvement. The patients received concurrent benznidazole treatment and antiretroviral therapy, showing good response. Improvement in morbidity and mortality due to early treatment makes this treatment appropriate for coinfected patients.

Keywords: Chagas disease; HIV; benznidazole; coinfection; treatment.