Slow growth causes bacterial persistence

Sci Signal. 2019 Jul 30;12(592):eaay1167. doi: 10.1126/scisignal.aay1167.

Abstract

Bacterial persisters survive antibiotic treatment and can cause chronic infections. In this issue of Science Signaling, Pontes and Groisman suggest that there is no specific molecular pathway responsible for persister formation in Salmonella and that slow growth is the decisive factor.

Publication types

  • Review
  • Comment

MeSH terms

  • Anti-Bacterial Agents
  • Drug Resistance, Microbial
  • Salmonella enterica*

Substances

  • Anti-Bacterial Agents