Current practices in the delivery of pharmacogenomics: Impact of the recommendations of the Pharmacy Practice Model Summit

Am J Health Syst Pharm. 2019 Apr 8;76(8):521-529. doi: 10.1093/ajhp/zxz024.

Abstract

Purpose: This report examines and evaluates pharmacogenomics as an emerging science as it relates to the Practice Advancement Initiative and its predecessor the Pharmacy Practice Model Initiative's consensus statements for optimal pharmacy practice models.

Summary: Pharmacogenomics is one of many emerging sciences to impact medication management and delivery of patient care. Increasingly, biomarkers are included in drug labeling and can assist pharmacists with personalizing medicine to optimize patient therapies and avoid adverse effects. The 2011 ASHP Pharmacy Practice Model Summit generated a list of 147 consensus statements for optimal pharmacy practice. Of these, 1 statement explicitly describes adjustment of drug regimens based on genetic factors as an essential activity of pharmacist-provided drug regimens, and 9 other statements provide additional support for incorporation of this emerging science into all aspects of patient care provided by pharmacists. We describe 4 institutions that have made significant inroads to implementing pharmacogenomics, to provide a framework and serve as resources for other institutions initiating their own pharmacogenomics implementation journeys.

Conclusion: Through prioritized efforts of the pharmacy profession and health care institutions, pharmacogenomics will be disseminated and implemented, and the goal of the Pharmacy Practice Model Initiative's consensus statements of improving health care using patients' genetic characteristics will be realized.

Keywords: pharmacogenetics; pharmacogenomics; pharmacy; pharmacy service/hospital; precision medicine.

MeSH terms

  • Consensus Development Conferences as Topic*
  • Health Plan Implementation
  • Humans
  • Models, Organizational*
  • Pharmaceutical Services / organization & administration*
  • Pharmaceutical Services / trends
  • Pharmacists
  • Pharmacogenetics / organization & administration*
  • Pharmacogenetics / trends
  • Precision Medicine / trends*
  • Professional Role