Objective: To investigate the medium-term curative effect of transjugular intrahepatic portosystemic shunt (TIPS) through jugular vein with covered Viatorr stent. Methods: Data of 105 consecutive patients with covered Viatorr stent of our hospital was retrospectively analyzed. Follow-up was performed after surgery, and color Doppler was reviewed to evaluate the efficacy of TIPS. Results: Transjugular intrahepatic shunt was successfully established in all patients. The pressure gradients of portal vein before and after operation were 22.33 ± 6.4 mmHg and 9.78 ± 4.9 mmHg, respectively,P< 0.01, and the difference was statistically significant. The follow-up period ranged from 12.7 to 15.6 months, with an average of 13.09 ± 1.4 month. Total bilirubin and coagulation time increased after operation, but there was no significant difference in total bilirubin and coagulation time at 1, 3, 6 and 12 months after operation. The patency rate of shunt was 100%, 99.05%, 99.05% and 99.05% at 1, 3, 6 and 12 months after operation. The incidence of hepatic encephalopathy was 34.2%, 29.5%, 19.1% and 14.3% respectively. The recurrence rate of symptoms was 0%. Conclusion: Patients with cirrhotic portal hypertension who underwent TIPS with covered Viatorr stent had a lower rate of restenosis, improved liver function, and a lower incidence of severe hepatic encephalopathy. However, the long-term efficacy needs further observation.
目的： 探讨经颈静脉肝内门体静脉分流术（TIPS）采用Viatorr覆膜支架建立分流道的中期疗效。 方法： 回顾性分析南方医院连续105例采用Viatorr覆膜支架建立TIPS分流道患者资料。术后进行随访，复查彩色多普勒，评价TIPS疗效。 结果： 所有患者均成功建立肝内分流道。术前、术后门静脉压力梯度分别为（22.33±6.4）mmHg、（9.78±4.9）mmHg，P < 0.01，差异有统计学意义。随访12.7～15.6（13.09±1.4）个月。术后总胆红素及凝血时间较术前升高，术后1、3、6、12个月总胆红素及凝血时间差异无统计学意义。术后1、3、6、12个月分流道通畅率分别为100％、99.05％、99.05％、99.05%，肝性脑病的发生率分别为34.2%、29.5%、19.1%、14.3%，症状复发率均为0。 结论： 肝硬化门静脉高压患者采用Viatorr覆膜支架行TIPS治疗的再狭窄率低，肝功能影响小，严重肝性脑病发生率低，长期疗效有待进一步观察。.
Keywords: Cirrhosis; Transjugular intrahepatic portosystemic shunt; Treatment outcome; Viatorr covered stent.