New/Revised Entities in Gastrointestinal Lymphoproliferative Disorders

Sarmad H Jassim; Lauren B Smith

doi:10.1016/j.path.2019.03.011

New/Revised Entities in Gastrointestinal Lymphoproliferative Disorders

Surg Pathol Clin. 2019 Sep;12(3):733-743. doi: 10.1016/j.path.2019.03.011. Epub 2019 May 23.

Authors

Sarmad H Jassim¹, Lauren B Smith²

Affiliations

¹ Pathology Department, University of Michigan, 2800 Plymouth Road, North Campus Research Complex, Building 36, Ann Arbor, MI, USA.
² Pathology Department, University of Michigan, 2800 Plymouth Road, North Campus Research Complex, Building 36, Ann Arbor, MI, USA. Electronic address: lbsmith@med.umich.edu.

PMID: 31352985
DOI: 10.1016/j.path.2019.03.011

Abstract

The gastrointestinal tract is a common extranodal site of involvement by lymphomas. These may be diagnostically challenging because they can mimic a variety of benign conditions and may be difficult to subclassify when malignant. The classification of gastrointestinal lymphomas is an evolving area with some recent changes. Although some of these entities are rare, they are important to recognize because of the variable clinical presentations, comorbidities, and treatment implications. This article explores new and revised entities in gastrointestinal lymphoproliferative disorders.

Keywords: EATL; Enteropathy-associated; Lymphoma; MEITL; Non-Hodgkin.

Publication types

Review

MeSH terms

Celiac Disease / complications
Chronic Disease
Diagnosis, Differential
Gastrointestinal Neoplasms / diagnosis*
Gastrointestinal Neoplasms / genetics
Gastrointestinal Neoplasms / therapy
Humans
Lymphoproliferative Disorders / diagnosis*
Lymphoproliferative Disorders / genetics
Lymphoproliferative Disorders / therapy
Prognosis