Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function

Leukemia. 2019 Dec;33(12):2962-2966. doi: 10.1038/s41375-019-0528-3. Epub 2019 Jul 26.

¹ Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
² Obstetric Intensive Care Center, The Institute of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200233, China.
³ Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
⁴ Department of Medical and Molecular Genetics, Center for Computational Biology and Bioinformatics (CCBB), Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
⁵ Department of BioHealth Informatics, School of Informatics and Computing, Indiana University Purdue University Indianapolis (IUPUI), Indianapolis, IN, 46202, USA.
⁶ Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. hbroxmey@iupui.edu.
⁷ Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. jybinguo@shsmu.edu.cn.

^# Contributed equally.

No abstract available

Publication types