Curcumin has recently attracted much attention due to the wide range of its physiological actions such as anti-tumor, anti-inflammatory, anti-thrombotic, anti-diabetic and anti-microbial effects. This phytochemical can be used as a sensing material for the detection of chemicals due to its optical properties as a fluorescent polyphenol. Curcumin and its derivatives can make complexes with many cations such as Cu2+, Fe2+, Hg2+, Pt2+, Re3+ and Al3+via bearing 1,3-diketones with keto-enol isomerization. The complexation of curcumin with certain metal ions leads to its solubility in water and producing various hues of colors as well as cytotoxic and antimicrobial effects. Curcumin can also form complexes with certain metal ions and thus serve as a chelating agent for anions such as ClO-, CN-, F- and S2-. Moreover, conjugation of curcumin with some organic compounds such as cysteine and poly-glycerol acrylate provides an efficient fluorescence detection system for picric acid and 2-vinyl pyridine in aqueous media. In this review, we focused on curcumin as a key element in a membrane composition of chemical sensors. In addition, the latest sensing platforms based on curcumin and its derivatives are briefly described.
Keywords: Anions; Cations; Complex; Curcumin; Ligand; Organic; Sensor.
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