Pituitary Hyperplasia in Severe Primary Hypothyroidism: A Case Report and Review of the Literature

Prateek Shukla; Ketan R Bulsara; Pooja Luthra

doi:10.1155/2019/2012546

Pituitary Hyperplasia in Severe Primary Hypothyroidism: A Case Report and Review of the Literature

Case Rep Endocrinol. 2019 Jun 25:2019:2012546. doi: 10.1155/2019/2012546. eCollection 2019.

Authors

Prateek Shukla¹, Ketan R Bulsara^{2

3}, Pooja Luthra^{2

4}

Affiliations

¹ Division of Internal Medicine, UConn Health Center, Farmington, CT 06030, USA.
² University of Connecticut School of Medicine, Farmington, CT 06030, USA.
³ Division of Neurosurgery, UConn Health Center, Farmington, CT 06030, USA.
⁴ Division of Endocrinology and Metabolism, UConn Health Center, Farmington, CT 06030, USA.

Abstract

Pituitary hyperplasia is commonly present but remains largely undiagnosed in primary hypothyroidism. It is easily reversible with thyroid replacement therapy. If imaging is performed prior to biochemical evaluation, then patients may undergo pituitary surgery. We present the case of a 34-year-old female with profound primary hypothyroidism and secondary pituitary hyperplasia that resolved after thyroid hormone supplementation. We will discuss the current literature regarding pituitary hyperplasia in primary hypothyroidism in adults.

Publication types

Case Reports