[Serious neurological compromise due to vitamin B12 deficiency in infants of vegan and vegetarian mothers]

Arch Argent Pediatr. 2019 Aug 1;117(4):e420-e424. doi: 10.5546/aap.2019.e420.
[Article in Spanish]

Abstract

Vitamin B12 deficiency is one of the most serious complications of vegetarianism and its variants. Infants born to vegan mothers are at greater risk of serious deficiency, being more vulnerable to their effects. B12 deficiency is not usually suspected by the pediatrician in healthy infants with neurological symptoms. The manifestations are nonspecific: apathy, rejection of food and loss of maturational patterns. A nutritional history of the mother, mainly if she is vegetarian, to estimate her reserves is fundamental to detect risk of deficiency of this vitamin in the small child. The objective of this work is to describe a group of infants, children of vegan mothers, with B12 deficiency and serious neurological compromise: central apneas, seizures, hypotonia, loss of connection with the environment and maturational patterns. Our purpose is to alert about the importance of supplying vegan mothers with B12 before conception until the end of breastfeeding.

La deficiencia de vitamina B12 es una de las complicaciones más graves del vegetarianismo. Los lactantes hijos de madres veganas tienen mayor riesgo de deficiencia grave y son más lábiles ante sus efectos. La deficiencia de B12 no es, por lo general, sospechada por el pediatra en lactantes previamente sanos con síntomas neurológicos, ya que las manifestaciones iniciales son inespecíficas: apatía, rechazo del alimento y pérdida de pautas madurativas. La anamnesis nutricional es fundamental para detectar riesgo de déficit de esta vitamina en lactantes. El objetivo de este trabajo es describir a un grupo de lactantes, hijos de madres veganas, con déficit de B12 y compromiso neurológico grave: apneas centrales, convulsiones, hipotonía, pérdida de conexión con el medio y de pautas madurativas. Nuestro propósito es alertar sobre la importancia de suplir B12 a las madres veganas desde antes de la concepción hasta el fin de la lactancia.

Keywords: Infant; Neurological disorders; Pediatrics; Vegetarianism; Vitamin B12 deficiency.

MeSH terms

  • Diet, Vegetarian / adverse effects*
  • Female
  • Humans
  • Infant, Newborn
  • Maternal Behavior
  • Nervous System Diseases / etiology*
  • Pregnancy
  • Pregnancy Complications / etiology*
  • Vitamin B 12 Deficiency / etiology*