Complications and reproductive outcome after uterine artery embolization for retained products of conception

J Obstet Gynaecol Res. 2019 Oct;45(10):2007-2014. doi: 10.1111/jog.14067. Epub 2019 Jul 23.

Abstract

Aim: The purpose of this study was to evaluate the complications and reproductive outcome after uterine artery embolization (UAE) for retained products of conception (RPOC).

Methods: This was a retrospective medical-records review study of 57 women treated for RPOC. Participants were divided into two groups: women who underwent treatment with UAE (UAE group: n = 32, 56.1%) and those without UAE (control group: n = 25, 43.9%). The complications and reproductive outcomes were compared between the two groups. Information on subsequent pregnancies and their outcomes was available for 30 women who attempted to conceive.

Results: There were no significant differences in the interval from the last delivery or abortion (40.1 ± 3.4 vs 51.0 ± 5.1 months, respectively; P = 0.16), the rate of severe bleeding under hysteroscopy (18.5 vs 9.1%, respectively; P = 0.65), the conception rate (58.8 vs 61.5%, respectively; P = 1.0) and mean time to conception (9.9 ± 1.6 vs 11.0 ± 2.9 months, respectively; P = 0.17) in women in the UAE group compared with those in the control group. Rates of post-partum hemorrhage (PPH) and manual removal of placenta (25.0% in the UAE group and 16.7% in the control group, respectively) were higher than the general population.

Conclusion: Selective UAE for RPOC may be a preferable procedure in women who are suspected as having a risk of severe bleeding under treatment. Women who were treated for RPOC, regardless of UAE, were at risk of PPH and difficulty in removing the placenta in future pregnancies.

Keywords: fertility; placental complications; retained products of conception; severe bleeding; uterine artery embolization.

MeSH terms

  • Abortion, Missed / therapy
  • Adult
  • Female
  • Humans
  • Postpartum Hemorrhage / etiology*
  • Pregnancy
  • Retrospective Studies
  • Uterine Artery Embolization / adverse effects*
  • Young Adult