Pearls and paradigms in Infective Keratitis

Rom J Ophthalmol. 2019 Apr-Jun;63(2):119-127.

Abstract

Infective Keratitis is a commonly encountered sight-threatening ocular emergency. In developing countries, it is a major cause of corneal blindness. Empirical treatment without microbiological work up often leads to treatment failure. Indiscriminate use of steroid antibiotic combination worsens the situation and makes further management challenging. The correct line of management can be potentially sight saving for both the ophthalmologist and the patient. This article on Infective keratitis has been written keeping best practices and protocols in mind. In a very simple and concise form, it focuses on the salient features of clinical presentation of infective keratitis and the stepwise approach to subsequent management in a patient. It explains in detail the way to perform corneal scraping, the importance of the same and further management based on microbiologically proven result. The management part includes indications and methods for medical as well as surgical intervention. We aimed to share our experience in the management of patients presenting with infective keratitis in the clinic.

Keywords: bacterial; culture; infective keratitis; management; microbiology; staining; treatment.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacteria / isolation & purification*
  • Cornea / microbiology*
  • Disease Management*
  • Eye Infections, Bacterial* / drug therapy
  • Eye Infections, Bacterial* / epidemiology
  • Eye Infections, Bacterial* / microbiology
  • Global Health
  • Humans
  • Incidence
  • Keratitis* / drug therapy
  • Keratitis* / epidemiology
  • Keratitis* / microbiology
  • Risk Factors

Substances

  • Anti-Bacterial Agents