Revisiting the Language of Glycoscience: Readers, Writers and Erasers in Carbohydrate Biochemistry

Chembiochem. 2020 Feb 3;21(3):423-427. doi: 10.1002/cbic.201900377. Epub 2019 Nov 4.

Abstract

The roles of carbohydrates in nature are many and varied. However, the lack of template encoding in glycoscience distances carbohydrate structure, and hence function, from gene sequence. This challenging situation is compounded by descriptors of carbohydrate structure and function that have tended to emphasise their complexity. Herein, we suggest that revising the language of glycoscience could make interdisciplinary discourse more accessible to all interested parties.

Keywords: carbohydrates; epigenetics; glycoscience vocabulary; glycosyl hydrolase; glycosylation; glycosyltransferase.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Carbohydrate Biochemistry
  • Carbohydrate Conformation
  • Carbohydrates / chemistry*
  • Carbohydrates / genetics
  • Glycosylation
  • Models, Molecular

Substances

  • Carbohydrates