Lindermyrrhin, a novel 3,4-dihydroisocoumarin from Lindera myrrha roots

Nat Prod Res. 2021 Apr;35(7):1122-1126. doi: 10.1080/14786419.2019.1641813. Epub 2019 Jul 17.

Abstract

A novel 3,4-dihydroisocoumarin, lindermyrrhin (1), along with three known compounds, quercetin (2), northalifoline (3) and N-formyl-laurolitsine (4) were isolated from the roots of Lindera myrrha. The structure of compound 1 was identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. The novel compound 1 represents the first 3,4-dihydroisocoumarin bearing a 2-hydroxyisopropyl substituent at C-3.

Keywords: 3,4-dihydroisocoumarin; Lauraceae; Lindera myrrha; lindermyrrhin.

MeSH terms

  • Carbon-13 Magnetic Resonance Spectroscopy
  • Isocoumarins / chemistry
  • Isocoumarins / pharmacology*
  • Lindera / chemistry*
  • Plant Roots / chemistry*
  • Proton Magnetic Resonance Spectroscopy

Substances

  • Isocoumarins