Intact Mycobacterium leprae Isolated from Placenta of a Pregnant Woman, China

Emerg Infect Dis. 2019 Aug;25(8):1604-1607. doi: 10.3201/eid2508.190114.

Abstract

Whether Mycobacterium leprae transmits from placenta to fetus remains unknown. We describe the case of a pregnant woman with untreated histoid leproma. Although her newborn was healthy, laboratory examination revealed intact M. leprae present in the placenta, suggesting that the placental barrier might prevent vertical dissemination of M. leprae.

Keywords: China; Mycobacterium leprae; placental barrier; pregnant woman; tuberculosis and other mycobacteria.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Biopsy
  • China / epidemiology
  • Female
  • Humans
  • Leprosy / diagnosis*
  • Leprosy / epidemiology
  • Leprosy / microbiology*
  • Mycobacterium leprae / isolation & purification*
  • Placenta / microbiology*
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / microbiology*
  • Pregnancy Outcome
  • Skin / pathology
  • Treatment Outcome
  • Ultrasonography

Substances

  • Antitubercular Agents