A cystic fibrosis child with lung function decline

J Cyst Fibros. 2019 Nov;18(6):e62-e64. doi: 10.1016/j.jcf.2019.06.015. Epub 2019 Jul 9.

Abstract

Respiratory infections are a major threat to cystic fibrosis patients. Besides bacteria, many fungi colonize the cystic fibrosis respiratory tract where an important fungal biota has been described. We report here the case of a 7-year-old cystic fibrosis child with pulmonary exacerbation and Arthrographis kalrae isolated from bronchoalveolar lavage fluid. To the best of our knowledge, this is the first reported case of lung infection due to Arhtrographis kalrae in a cystic fibrosis pediatric patient.

Keywords: Arthrographis kalrae; BAL; Cystic_fibrosis; Lung_function_decline; Pulmonary_exacerbation.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / administration & dosage
  • Ascomycota / isolation & purification*
  • Bronchoalveolar Lavage / methods
  • Bronchoalveolar Lavage Fluid / microbiology*
  • Child
  • Cystic Fibrosis* / diagnosis
  • Cystic Fibrosis* / drug therapy
  • Cystic Fibrosis* / microbiology
  • Cystic Fibrosis* / physiopathology
  • Humans
  • Itraconazole / administration & dosage*
  • Lung / diagnostic imaging
  • Lung / microbiology
  • Lung Diseases, Fungal* / diagnosis
  • Lung Diseases, Fungal* / drug therapy
  • Lung Diseases, Fungal* / physiopathology
  • Male
  • Respiratory Function Tests / methods*
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Itraconazole