Effective asymmetric Michael addition of anthrone to nitroalkenes using chiral tetraoxacalix[2]arene[2]triazines as organocatalysts

Hayriye Nevin Genc

doi:10.1002/chir.23108

Effective asymmetric Michael addition of anthrone to nitroalkenes using chiral tetraoxacalix[2]arene[2]triazines as organocatalysts

Chirality. 2019 Sep;31(9):711-718. doi: 10.1002/chir.23108. Epub 2019 Jul 11.

Author

Hayriye Nevin Genc¹

Affiliation

¹ Department of Science Education, A. K. Education Faculty, Necmettin Erbakan University, Konya, Turkey.

PMID: 31294902
DOI: 10.1002/chir.23108

Abstract

Novel chiral secondary amines bearing a tetraoxacalix[2]arene[2]triazine scaffold were created and used for catalytic asymmetric Michael reaction of anthrone with nitroalkenes. The relevant adducts were obtained in good to excellent yields (82%-98%) and enantioselectivities (75%-98%).

Keywords: Michael addition; anthrone; nitroalkenes; tetraoxacalix[2]arene[2]triazine.