Measurement of Rn-219 with Alphaguard radon monitors

Appl Radiat Isot. 2019 Sep:151:310-316. doi: 10.1016/j.apradiso.2019.03.041. Epub 2019 Apr 1.

Abstract

The alpha-emitting radionuclide Ra-223 is used in nuclear medicine in form of the commercially available radiopharmaceutical "Xofigo". The direct progeny of Ra-223 is Rn-219, a noble gas with a half-life of approx. four seconds, that might be exhaled by patients treated with Ra-223. For assessing the exhalation of Rn-219, a radon monitor calibrated for this isotope is necessary. This work investigates on the response of the commercially available Alphaguard radon monitor to Rn-219 and proposes for the first time a factor for the calculation of the Rn-219-concentration in the instrument's measurement chamber from the instrument reading suitable for estimating patients exhalations.

Keywords: Alphaguard; Nuclear medicine; Rn-219 measurement.

MeSH terms

  • Calibration
  • Humans
  • Radiation Monitoring / instrumentation*
  • Radon Daughters / analysis*

Substances

  • Radon Daughters