[IL-1RAP as a candidate for CAR T-cells immunotherapy]

MeSH terms

• Animals
• Antibodies, Monoclonal / genetics
• Antibodies, Monoclonal / therapeutic use*
• Antigens, Neoplasm / immunology
• Biomarkers, Tumor / genetics
• Biomarkers, Tumor / immunology
• Biomarkers, Tumor / metabolism
• Caspase 9 / genetics
• Fusion Proteins, bcr-abl / metabolism
• Gene Expression Regulation, Neoplastic
• Genes, Transgenic, Suicide
• Hematologic Neoplasms / therapy*
• Hematopoietic Stem Cells / cytology
• Hematopoietic Stem Cells / metabolism
• Humans
• Immunotherapy, Adoptive / adverse effects
• Immunotherapy, Adoptive / methods*
• Interleukin-1 Receptor Accessory Protein / genetics
• Interleukin-1 Receptor Accessory Protein / immunology
• Interleukin-1 Receptor Accessory Protein / metabolism*
• Killer Cells, Natural / immunology
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / metabolism
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
• Leukemia, Myeloid, Acute / genetics
• Leukemia, Myeloid, Acute / metabolism
• Leukemia, Myeloid, Acute / therapy
• Lymphocytes, Tumor-Infiltrating / immunology
• Lymphocytes, Tumor-Infiltrating / metabolism*
• Lymphocytes, Tumor-Infiltrating / transplantation
• Mice
• Mice, Inbred BALB C
• Neoplasms / metabolism
• Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism
• Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
• Receptors, Chimeric Antigen / immunology
• Receptors, Chimeric Antigen / metabolism*