Animal Models of Eating Disorders

Methods Mol Biol. 2019:2011:297-314. doi: 10.1007/978-1-4939-9554-7_17.

Abstract

Eating disorders (EDs) include a range of chronic and disabling pathologies characterized by persistent maladaptive eating habits and/or behaviors aimed at controlling body shape and size, with important consequences on physical health. Different animal models of EDs have been developed to investigate pharmacological, environmental, and genetic determinants that contribute to the development and maintenance of these disorders as well as for the identification of potential therapeutic targets. In this chapter, we will provide an overview of the most useful animal models of EDs, focusing mainly on those used to study anorexia nervosa and binge eating disorder.

Keywords: Animal models; Anorexia nervosa; Binge eating disorder; Eating disorders; Palatable food; Physical activity; Stress.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animal Feed
  • Animals
  • Disease Models, Animal*
  • Disease Susceptibility*
  • Feeding Behavior
  • Feeding and Eating Disorders / diagnosis
  • Feeding and Eating Disorders / etiology*
  • Female
  • Rats