Facile construction of boranil complexes with aggregation-induced emission characteristics and their specific lipid droplet imaging applications

Chem Commun (Camb). 2019 Jul 16;55(58):8494-8497. doi: 10.1039/c9cc04041b.

Abstract

A rational strategy was reported to construct boranil complexes (DPFB derivatives) with unique aggregation-induced emission effects by installing phenyl rings in the anil ligand as the intramolecular rotors. In view of the good biocompatibility and suitable lipophilicity, DPFB derivatives can serve as excellent fluorescent probes for specific imaging of lipid droplets in living cells and yolk lipids in zebrafish.

MeSH terms

  • Aniline Compounds / chemical synthesis
  • Aniline Compounds / chemistry*
  • Animals
  • Boron Compounds / chemical synthesis
  • Boron Compounds / chemistry*
  • Coordination Complexes / chemical synthesis
  • Coordination Complexes / chemistry*
  • Fluorescence
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Ligands
  • Lipid Droplets / metabolism*
  • Microscopy, Confocal / methods
  • Molecular Structure
  • Zebrafish

Substances

  • Aniline Compounds
  • Boron Compounds
  • Coordination Complexes
  • Fluorescent Dyes
  • Ligands