Adrenocortical Cancer Treatment

Samuel E Long; Barbra S Miller

doi:10.1016/j.suc.2019.04.012

Adrenocortical Cancer Treatment

Surg Clin North Am. 2019 Aug;99(4):759-771. doi: 10.1016/j.suc.2019.04.012. Epub 2019 May 27.

Authors

Samuel E Long¹, Barbra S Miller²

Affiliations

¹ Division of Endocrine Surgery, Department of Surgery, University of Michigan, 2920H Taubman Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: selong@med.umich.edu.
² Division of Endocrine Surgery, Department of Surgery, University of Michigan, 2920H Taubman Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA.

PMID: 31255205
DOI: 10.1016/j.suc.2019.04.012

Abstract

Adrenocortical cancer is a rare disease. Prognosis remains poor but is improving. In this article, initial presentation, biochemical and imaging evaluation, surgical approach to resection, and postoperative care are reviewed. Prognosis, patterns of recurrence, treatment of metastatic disease using medical therapy and other surgical and nonsurgical therapies are discussed.

Keywords: Adrenal cancer; Adrenalectomy; Adrenocortical carcinoma; Cancer; Cortisol; Mitotane; Surgery.

Publication types

Review

MeSH terms

Adrenal Cortex Neoplasms / therapy*
Adrenalectomy / methods*
Adrenocortical Carcinoma / therapy*
Antineoplastic Agents / therapeutic use*
Chemotherapy, Adjuvant
Humans
Treatment Outcome

Substances

Antineoplastic Agents