Chelidonine Induces Caspase-Dependent and Caspase-Independent Cell Death through G2/M Arrest in the T98G Human Glioblastoma Cell Line

Yeon-Kyeong Lee; Ki Won Lee; Minju Kim; Yerin Lee; Jiyun Yoo; Cheol Hwangbo; Ki Hun Park; Kwang Dong Kim

doi:10.1155/2019/6318179

Chelidonine Induces Caspase-Dependent and Caspase-Independent Cell Death through G_2/M Arrest in the T98G Human Glioblastoma Cell Line

Evid Based Complement Alternat Med. 2019 May 26:2019:6318179. doi: 10.1155/2019/6318179. eCollection 2019.

Authors

Yeon-Kyeong Lee¹, Ki Won Lee¹, Minju Kim¹, Yerin Lee¹, Jiyun Yoo^{1

2}, Cheol Hwangbo², Ki Hun Park¹, Kwang Dong Kim^{1

2

3}

Affiliations

¹ Division of Applied Life Science (BK21Plus), Gyeongsang National University, Jinju 660-701, Republic of Korea.
² Division of Life Science, Gyeongsang National University, Jinju 660-701, Republic of Korea.
³ PMBBRC, Gyeongsang National University, Jinju 660-701, Republic of Korea.

Abstract

Chelidonium majus L. (family Papaveraceae), commonly known as greater celandine or tetterwort, has been reported to have antibacterial and anticancer effects and chelidonine is known as a functional metabolite extracted from C.