Complete Sequence and Annotation of the Mycoplasma phocicerebrale Strain 1049T Genome

Salvatore Frasca Jr; Jessy Castellanos Gell; Gerald F Kutish; Dina L Michaels; Daniel R Brown

doi:10.1128/MRA.00514-19

Complete Sequence and Annotation of the Mycoplasma phocicerebrale Strain 1049^T Genome

Microbiol Resour Announc. 2019 Jun 20;8(25):e00514-19. doi: 10.1128/MRA.00514-19.

Authors

Salvatore Frasca Jr¹, Jessy Castellanos Gell¹, Gerald F Kutish², Dina L Michaels³, Daniel R Brown⁴

Affiliations

¹ Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
² Department of Pathobiology and Veterinary Science and Center of Excellence for Vaccine Research, University of Connecticut, Storrs, Connecticut, USA.
³ Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
⁴ Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA drbrown@ufl.edu.

Abstract

The Mycoplasma phocicerebrale genome was analyzed to better understand this opportunistic pathogen. Amplification with ϕ29 polymerase was used to generate enough genomic DNA for large-insert library construction. Like other mycoplasmas from seals, M. phocicerebrale encodes an immunosuppressor that may predispose susceptibility to infection or influence intercurrent diseases of affected hosts.