Guanosine-based thermotropic liquid crystals with tunable phase structures and ion-responsive properties

Zhaohui Huang; Xueyuan Li; Mengjun Chen; Yihan Liu; Xiuping Sun; Aixin Song; Jingcheng Hao

doi:10.1016/j.jcis.2019.06.041

Guanosine-based thermotropic liquid crystals with tunable phase structures and ion-responsive properties

J Colloid Interface Sci. 2019 Oct 1:553:269-279. doi: 10.1016/j.jcis.2019.06.041. Epub 2019 Jun 13.

Authors

Zhaohui Huang¹, Xueyuan Li¹, Mengjun Chen¹, Yihan Liu¹, Xiuping Sun¹, Aixin Song², Jingcheng Hao¹

Affiliations

¹ Key Laboratory of Colloid and Interface Chemistry & Key Laboratory of Special Aggregated Materials, Shandong University, Ministry of Education, Jinan, Shandong Province 250100, China.
² Key Laboratory of Colloid and Interface Chemistry & Key Laboratory of Special Aggregated Materials, Shandong University, Ministry of Education, Jinan, Shandong Province 250100, China. Electronic address: songaixin@sdu.edu.cn.

PMID: 31212227
DOI: 10.1016/j.jcis.2019.06.041

Abstract

In this work, the thermotropic liquid crystals (LCs) composed of a biological molecule, guanosine 5'-monophosphate disodium salt (GMP), with different cationic surfactants were reported. When GMP interacted with the surfactants, the length of the surfactant alkyl chains was found to be of great importance in modulating the LC phase. The smectic A (SmA) phase and columnar rectangular (Col_r) phase were formed upon increasing the length of the aliphatic chains due to the enlargement of the steric hindrance. Interestingly, K⁺ ions were observed to cause the phase transition of LCs from the SmA or Col_r mesophase to a columnar hexagonal (Col_h) mesophase in the GMP-surfactant complexes, which was attributed to the formation of G-quadruplexes. Accordingly, the chirality and fluorescence properties of the complexes also exhibited K⁺-responsive characters as the phase transition of the LCs emerged. Compared with the reported LCs containing guanosine groups, the thermotropic LCs with high elasticity and tunable mesophase structures in this study are easy to be prepared and are hopeful to provide potential applications for constructing stimuli-responsive luminescent materials, biocatalysis and biosensor devices.

Keywords: Guanosine; Self-assembly; Stimuli-responsive; Surfactant; Thermotropic liquid crystals.