Pseudomonas putida KT2440 is HV1 certified, not GRAS

Linde F C Kampers; Rita J M Volkers; Vitor A P Martins Dos Santos

doi:10.1111/1751-7915.13443

Pseudomonas putida KT2440 is HV1 certified, not GRAS

Microb Biotechnol. 2019 Sep;12(5):845-848. doi: 10.1111/1751-7915.13443. Epub 2019 Jun 14.

Authors

Linde F C Kampers¹, Rita J M Volkers¹, Vitor A P Martins Dos Santos^{1

2}

Affiliations

¹ Laboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Stippeneng 4, 6708, Wageningen, The Netherlands.
² Lifeglimmer GmbH, Markelstr. 38, 12163, Berlin, Germany.

Abstract

Pseudomonas putida is rapidly becoming a workhorse for industrial production due to its metabolic versatility, genetic accessibility and stress-resistance properties. The P. putida strain KT2440 is often described as Generally Regarded as Safe, or GRAS, indicating the strain is safe to use as food additive. This description is incorrect. P. putida KT2440 is classified by the FDA as HV1 certified, indicating it is safe to use in a P1 or ML1 environment.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Food Microbiology / methods
Food Microbiology / standards*
Food Safety / methods*
Industrial Microbiology / methods
Industrial Microbiology / standards*
Pseudomonas putida / growth & development
Pseudomonas putida / metabolism
Pseudomonas putida / pathogenicity*
United States
United States Food and Drug Administration