Free-standing 2D nanorafts by assembly of 1D nanorods for biomolecule sensing

Ren Cai; Yaping Du; Dan Yang; Guohua Jia; Bowen Zhu; Bo Chen; Yifan Lyu; Kangfu Chen; Dechao Chen; Wei Chen; Lu Yang; Yuliang Zhao; Zhuo Chen; Weihong Tan

doi:10.1039/c9nr02636c

Free-standing 2D nanorafts by assembly of 1D nanorods for biomolecule sensing

Nanoscale. 2019 Jul 7;11(25):12169-12176. doi: 10.1039/c9nr02636c. Epub 2019 Jun 14.

Authors

Ren Cai¹, Yaping Du², Dan Yang³, Guohua Jia⁴, Bowen Zhu³, Bo Chen³, Yifan Lyu⁵, Kangfu Chen⁶, Dechao Chen⁴, Wei Chen⁴, Lu Yang⁷, Yuliang Zhao⁸, Zhuo Chen⁹, Weihong Tan¹⁰

Affiliations

¹ Molecular Sciences and Biomedicine Laboratory (MBL), State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China. tan@chem.ufl.edu zhuochen@hnu.edu.cn and Department of Chemistry and Department of Physiology and Functional Genomics, Center for Research at the Bio/Nano Interface, Shands Cancer Center, UF Genetics Institute, McKnight Brain Institute, University of Florida, Gainesville, FL 32611-7200, USA.
² School of Material Science and Engineering, Nankai University, Tianjin 300350, China.
³ School of Materials Science and Engineering, Nanyang Technological University, 639798, Singapore.
⁴ Nanochemistry Research Institute, Department of Chemistry, Curtin University, P.O. Box U1987, Perth, WA 6845, Australia.
⁵ Molecular Sciences and Biomedicine Laboratory (MBL), State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China. tan@chem.ufl.edu zhuochen@hnu.edu.cn and Institute of Molecular Medicine (IMM), Renji Hospital, Shanghai Jiao Tong University School of Medicine, and College of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, China.
⁶ Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, Florida 32611-6250, USA.
⁷ Department of Chemistry and Department of Physiology and Functional Genomics, Center for Research at the Bio/Nano Interface, Shands Cancer Center, UF Genetics Institute, McKnight Brain Institute, University of Florida, Gainesville, FL 32611-7200, USA.
⁸ National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100049, China.
⁹ Molecular Sciences and Biomedicine Laboratory (MBL), State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China. tan@chem.ufl.edu zhuochen@hnu.edu.cn.
¹⁰ Molecular Sciences and Biomedicine Laboratory (MBL), State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China. tan@chem.ufl.edu zhuochen@hnu.edu.cn and Department of Chemistry and Department of Physiology and Functional Genomics, Center for Research at the Bio/Nano Interface, Shands Cancer Center, UF Genetics Institute, McKnight Brain Institute, University of Florida, Gainesville, FL 32611-7200, USA and Institute of Molecular Medicine (IMM), Renji Hospital, Shanghai Jiao Tong University School of Medicine, and College of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, China.

Abstract

Novel materials from self-assembled nanocrystals hold great promise for applications ranging from inorganic catalysis to bio-imaging. However, because of the inherent anisotropic properties, it is challenging to assemble one-dimensional (1D) nanorods into higher-order structures (e.g. 2D sheets or 3D networks) without any support. Here, we have developed a facile strategy for the direct self-assembly of 1D nanorods into free-standing 2D nanorafts with lateral dimensions up to several micrometers. As a general approach, 2D nanorafts with diverse compositions, e.g. MgF₂, WO₂, CdS, ZnS, and ZnSe nanorafts, have been fabricated from the assembly of their 1D building blocks. More importantly, these nanorafts show high stability even when dispersed in different solvents, making them suitable for various applications. Because of their high porosity and strong adsorption capability, MgF₂ nanorafts were investigated to illustrate the collective advantages generated from the assembly platform. Moreover, flexibility in the composition and structure of the building blocks demonstrated in this work will lead to next generation materials with rich functionalities.

MeSH terms

Biosensing Techniques*
Nanocomposites / chemistry*
Nanotubes / chemistry*

Grants and funding

R35 GM127130/GM/NIGMS NIH HHS/United States