Rupture of Hepatic Pseudoaneurysm Formed Nine Years after Carbon Ion Radiotherapy for Hepatocellular Carcinoma

Intern Med. 2019 Sep 15;58(18):2639-2643. doi: 10.2169/internalmedicine.2682-19. Epub 2019 Jun 7.

Abstract

An 83-year-old man with a history of carbon ion radiotherapy for hepatocellular carcinoma nine years ago presented to a primary care hospital with a fever and abdominal pain. He underwent computed tomography, which revealed the rupture of a hepatic pseudoaneurysm close to the fiducial marker for carbon ion radiotherapy and bleeding into the bile duct. He was successfully treated with transcatheter arterial embolization. Thereafter, re-rupture occurred from a site proximal to the first rupture, and this was treated similarly. It is necessary to be alert for not only tumor recurrence but also pseudoaneurysm occurrence after carbon ion radiotherapy.

Keywords: carbon ion radiotherapy; hepatocellular carcinoma; obstructive jaundice; pseudoaneurysm; rupture; transcatheter arterial embolization.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Aneurysm, False / therapy*
  • Carcinoma, Hepatocellular / pathology*
  • Embolization, Therapeutic / methods*
  • Humans
  • Liver Neoplasms / pathology*
  • Male
  • Recurrence
  • Rupture, Spontaneous / therapy*
  • Treatment Outcome