Neutrophil extracellular traps and low-density granulocytes are associated with the interferon signature in systemic lupus erythematosus, but not in antiphospholipid syndrome

Lucas L van den Hoogen; Maarten van der Linden; Linde Meyaard; Ruth D E Fritsch-Stork; Joel A van Roon; Timothy Rdj Radstake

doi:10.1136/annrheumdis-2019-215781

Neutrophil extracellular traps and low-density granulocytes are associated with the interferon signature in systemic lupus erythematosus, but not in antiphospholipid syndrome

Ann Rheum Dis. 2020 Oct;79(10):e135. doi: 10.1136/annrheumdis-2019-215781. Epub 2019 Jun 8.

Authors

Lucas L van den Hoogen^{1

2}, Maarten van der Linden², Linde Meyaard², Ruth D E Fritsch-Stork^{3

2}, Joel A van Roon^{3

2}, Timothy Rdj Radstake^{3

2}

Affiliations

¹ Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands L.L.vandenHoogen@umcutrecht.nl.
² Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
³ Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.

PMID: 31177097
DOI: 10.1136/annrheumdis-2019-215781

No abstract available

Keywords: Neutrophils; antiphospholipid antibodies; antiphospholipid syndrome; autoimmune diseases; disease activity; systemic lupus erythematosus.

Publication types

Letter
Comment

MeSH terms

Antiphospholipid Syndrome*
Extracellular Traps*
Granulocytes
Humans
Interferons
Lupus Erythematosus, Systemic*
Neutrophils
T-Lymphocytes

Substances

Interferons