Interleukin-17 receptor D: An orphan receptor finds a home in the skin

Sci Immunol. 2019 Jun 7;4(36):eaax0687. doi: 10.1126/sciimmunol.aax0687. Epub 2019 Jun 7.

Authors

Allison C Billi¹, Johann E Gudjonsson²

Affiliations

¹ Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
² Department of Dermatology, University of Michigan, Ann Arbor, MI, USA. johanng@med.umich.edu.

PMID: 31175177
DOI: 10.1126/sciimmunol.aax0687

Abstract

Interleukin-17 receptor D (IL-17RD) heterodimerizes with IL-17RA to form a receptor selective for the cytokine IL-17A.

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Publication types

Review
Comment

MeSH terms

Dermatitis*
Humans
Inflammation
Interleukin-17
Psoriasis*
Receptors, Interleukin-17

Substances

Interleukin-17
Receptors, Interleukin-17

Grants and funding

T32 AR007197/AR/NIAMS NIH HHS/United States